Research Opportunity: Emory University Studies Origins of Cleft Lip and Palate

The only way to learn more about the conditions that cause facial differences is through research. Many universities, hospitals, and organizations are conducting research on our genes to learn more about which DNA sequences may hold the answers to the "why" syndromes occur. 

To that end, Emory University's Leslie Lab created the Emory Cleft Project to learn more about the origins of cleft lip and palate at the genetic level.

Research study coordinator, Grace Carlock, states that "the study hopes to understand the different factors that contribute to craniofacial differences, including orofacial clefting. We do not yet understand the processes that give rise to these disorders but other studies point to personal genetic factors like family history of clefting and other medical conditions, and environmental factors like exposure to certain substances during pregnancy. The overall goal of the study is to develop a better understanding of genes related to orofacial clefts and how they interact with the environment, in order to improve treatment, management, and prevention of orofacial clefts."

Participants will be compensated for their time toward helping Emory researchers meet the goals outlined above. Carlock says that parents and children who choose to become involved will fill out "four online surveys that will take about 10-20 minutes each to complete, and a provide a saliva sample that can be collected in person or through the mail. For those who live in or near Emory University in Atlanta, GA, we would like to set up a study visit where we can collect the saliva sample and take 3-D photographs. We may also ask for 2-D photographs and medical records if needed." 

Principal investigator, Dr. Elizabeth Leslie says the goal is to expand "research participation on orofacial clefts to reach families who live in areas without active research." 

Compensation for the project participation is $25 for the online surveys and an additional $25 for saliva samples. The $50 will be given in the form of Amazon gift cards. Participation is voluntary. 

Learn more about the Emory Cleft Project on their website. If you are interested in participating, send them an email at [email protected] if you would like to participate.